Experience in prenatal ultrasound diagnosis of fetal microtia and associated abnormalities

Objective Prenatal ultrasound features, associated anomalies and genetic abnormalities of microtia cases were analyzed to explore the feasibility value prenatal for diagnosis microtia. Methods The ultrasonographic anomalies, chromosome examination results follow-up 81 fetuses with congenital retrospectively. Results Among diagnosed after birth, 2 missed on ultrasound, 1 case was as unilateral by but found be bilateral birth. Microtia accompanied an accessory auricle in 4 (4.94%) low-set ears 7 (8.64%). 22 (27.16%) complicated other structural including 11 (13.58%) cardiac (8.64%) soft marker 6 (7.41%) facial nervous system 3 (3.70%) urogenital digestive tract (2.47%) limb anomalies. Chromosome karyotype analysis gene detection performed 44 cases. Trisomy 18, trisomy 13, 21, pericentric inversion 9, partial loss heterozygosity 14, 22q11 microdeletion a normal cases, case, 34 respectively. Conclusion In summary, is often defects organs structures, especially heart face, important clinical significance.